Microsoft Copilot is the clear winner: 7.5/10 (B-tier) versus 6.5/10 (C-tier). Claude Mythos Preview isn't a bad tool, but on every category that drives the overall score, Microsoft Copilot comes out ahead. The tier gap is repeatable -- not methodology noise -- and the day-to-day experience reflects it.
On pricing, Microsoft Copilot starts free while Claude Mythos Preview requires a paid plan from day one (Invite only+). If you're testing the waters or running an occasional workload, that gap matters more than the score differential. Claude Mythos Preview starts at Invite only; Microsoft Copilot starts at $0. Compare what each entry tier actually unlocks before you compare list prices -- the limits matter more than the headline number.
By use case: pick Claude Mythos Preview when partner organizations in project glasswing doing cybersecurity research, defensive red-teaming, threat intelligence, or large-scale vulnerability triage. Pick Microsoft Copilot when users already deep in the microsoft ecosystem who want free gpt-4 access with web search built in. The two tools aren't fighting for the same person -- they're aiming at adjacent jobs that occasionally overlap. If you're squarely in Microsoft Copilot's lane, the tier-list ranking and the use-case fit point the same direction; if you're in Claude Mythos Preview's lane, the score gap matters less than the fit.
Bottom line: Microsoft Copilot is the better tool for most people right now. Pick Claude Mythos Preview only when partner organizations in project glasswing doing cybersecurity research, defensive red-teaming, threat intelligence, or large-scale vulnerability triage -- that's its lane, and inside that lane it still earns its place.